Motif ID: NFY{A,B,C}.p2

Z-value: 3.391


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
Nfya 18044 nuclear transcription factor-Y alpha
Nfyb 18045 nuclear transcription factor-Y beta
Nfyc 18046 nuclear transcription factor-Y gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfyachr17_-_485489730.451.8e-10Click!
Nfybchr10_-_822267740.367.1e-07Click!
Nfycchr4_-_1204981980.249.7e-04Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_98885428 110.825 NM_011623
 Top2a
topoisomerase (DNA) II alpha
chr6_+_124780226 74.686 Cdca3
cell division cycle associated 3
chr6_+_124780193 73.374 NM_013538
 Cdca3
cell division cycle associated 3
chr13_+_23666249 62.675 NM_178188
 Hist1h2ad
Hist1h2ai
histone cluster 1, H2ad
histone cluster 1, H2ai
chr14_-_68333666 55.527 NM_001110162
 Cdca2
cell division cycle associated 2
chr13_-_22127419 53.418 NM_175659
 Hist1h2ah
histone cluster 1, H2ah
chr9_-_70269246 50.099 Ccnb2
cyclin B2
chr14_+_47380287 46.918 Cdkn3
cyclin-dependent kinase inhibitor 3
chr10_-_68815606 46.171 NM_007659
 Cdk1
cyclin-dependent kinase 1
chr13_-_21879086 43.650 NM_178184
 Hist1h2an
histone cluster 1, H2an
chr11_+_71855939 43.211 NM_144526
 Fam64a
family with sequence similarity 64, member A
chr2_-_172195998 42.893 NM_011497
 Aurka
aurora kinase A
chr16_-_17125198 41.031 NM_183287
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr8_+_59990639 39.887 NM_008252
 Hmgb2
high mobility group box 2
chr14_+_47380215 39.493 NM_028222
 Cdkn3
cyclin-dependent kinase inhibitor 3
chr13_+_51740600 37.467 NM_025415
 Cks2
CDC28 protein kinase regulatory subunit 2
chr9_+_83728331 37.432 Ttk
Ttk protein kinase
chr13_+_51740804 37.266 Cks2
CDC28 protein kinase regulatory subunit 2
chr17_+_56443710 37.106 NM_001111078
NM_001111080
 Uhrf1

ubiquitin-like, containing PHD and RING finger domains, 1

chr17_+_56443766 36.563 Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 158 entries
Enrichment   P-value GO Accession GO Term
8.65 6.00e-03 GO:0006270 DNA-dependent DNA replication initiation
6.95 2.73e-03 GO:0045132 meiotic chromosome segregation
5.79 1.64e-05 GO:0016126 sterol biosynthetic process
5.70 6.93e-04 GO:0006695 cholesterol biosynthetic process
5.49 1.33e-05 GO:0000819 sister chromatid segregation
5.24 2.54e-04 GO:0000070 mitotic sister chromatid segregation
5.15 2.21e-02 GO:0031576 G2/M transition checkpoint
4.55 3.55e-06 GO:0034728 nucleosome organization
4.52 1.07e-12 GO:0007059 chromosome segregation
4.45 8.18e-05 GO:0006334 nucleosome assembly
4.40 1.22e-09 GO:0006323 DNA packaging
4.31 6.46e-12 GO:0071103 DNA conformation change
4.26 3.30e-05 GO:0065004 protein-DNA complex assembly
4.25 1.48e-05 GO:0071824 protein-DNA complex subunit organization
4.24 3.01e-02 GO:0008156 negative regulation of DNA replication
4.19 4.84e-25 GO:0000087 M phase of mitotic cell cycle
4.19 1.03e-04 GO:0031497 chromatin assembly
4.12 2.04e-23 GO:0000280 nuclear division
4.12 2.04e-23 GO:0007067 mitosis
4.03 4.99e-03 GO:0006261 DNA-dependent DNA replication

Gene overrepresentation in compartment category:

Showing 1 to 20 of 61 entries
Enrichment   P-value GO Accession GO Term
7.61 7.09e-04 GO:0000780 condensed nuclear chromosome, centromeric region
5.20 2.67e-02 GO:0045120 pronucleus
5.07 9.31e-10 GO:0000794 condensed nuclear chromosome
4.94 7.27e-04 GO:0000779 condensed chromosome, centromeric region
4.45 1.75e-12 GO:0000793 condensed chromosome
4.45 1.30e-05 GO:0030496 midbody
4.29 5.89e-05 GO:0016363 nuclear matrix
4.22 9.38e-04 GO:0000922 spindle pole
3.91 5.78e-05 GO:0034399 nuclear periphery
3.74 9.01e-07 GO:0000776 kinetochore
3.62 2.04e-14 GO:0044454 nuclear chromosome part
3.57 4.48e-10 GO:0000775 chromosome, centromeric region
3.53 6.75e-04 GO:0000792 heterochromatin
3.52 1.43e-15 GO:0000228 nuclear chromosome
3.39 3.85e-07 GO:0005819 spindle
3.33 2.77e-04 GO:0032993 protein-DNA complex
3.28 4.43e-02 GO:0000786 nucleosome
3.20 3.24e-25 GO:0044427 chromosomal part
3.15 2.40e-26 GO:0005694 chromosome
3.14 2.27e-02 GO:0034708 methyltransferase complex

Gene overrepresentation in function category:

Showing 1 to 20 of 38 entries
Enrichment   P-value GO Accession GO Term
10.30 1.22e-02 GO:0000400 four-way junction DNA binding
8.83 3.99e-02 GO:0004576 oligosaccharyl transferase activity
8.83 3.99e-02 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
7.42 2.94e-04 GO:0000217 DNA secondary structure binding
4.41 2.50e-02 GO:0003678 DNA helicase activity
3.71 3.68e-03 GO:0003697 single-stranded DNA binding
3.71 3.68e-03 GO:0043021 ribonucleoprotein binding
3.63 4.07e-05 GO:0042393 histone binding
2.61 4.29e-06 GO:0043566 structure-specific DNA binding
2.43 2.40e-02 GO:0016853 isomerase activity
2.37 1.34e-02 GO:0003690 double-stranded DNA binding
2.31 5.62e-04 GO:0003682 chromatin binding
2.10 5.64e-05 GO:0016563 transcription activator activity
2.07 3.21e-03 GO:0019901 protein kinase binding
1.99 8.49e-13 GO:0030528 transcription regulator activity
1.93 1.77e-24 GO:0003677 DNA binding
1.92 5.78e-03 GO:0008134 transcription factor binding
1.86 1.74e-02 GO:0016564 transcription repressor activity
1.82 5.27e-30 GO:0003676 nucleic acid binding
1.79 1.57e-06 GO:0001071 nucleic acid binding transcription factor activity